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• Functional annotation and validation of regulatory elements in the chicken genome.

  USDA-NIFA 2020-67015-31175 [$500,000] (2020-04-01~2023-03-31)

  Objectives: (1) Identify and annotate regulatory elements in chicken gut and reproductive tissues by integrating information from RNA-seq, ATAC-seq, and ChIP-seq; (2) Use lentiMPRA in a model cell line to functionally validate a set of enhancers; (3) Employ promoter capture Hi-C to identify target genes of enhancers. More importantly, this knowledge will greatly enhance precision genome selection, which will translate into significant improvements for US poultry producers and consumers.

  Project directors:

  • Huaijun Zhou, University of California, Davis

  Contact: Huaijun Zhou (hzhou@ucdavis.edu)

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