Whole genome analysis for QTL/association enrichment
Running...
Version: Enrich S: beta v0.8
Data:
Number of blood parameters traits:
20
Number of QTL / associations found:
298
Number of chromosomes where QTL / associations are found:
27
Chi-squared (χ2) test: are blood parameters traits over-represented on some chromosomes?
Chromosomes
Total χ2
df
p-values
FDR *
Size of χ2
Chromosome X
182.55280
26
1.834583e-25
1.238344e-24
Chromosome 1
796.31120
26
4.13783e-151
1.117214e-149
Chromosome 2
521.41180
26
1.290389e-93
1.161350e-92
Chromosome 3
521.41180
26
1.290389e-93
1.161350e-92
Chromosome 4
64.43200
26
4.136585e-05
6.980487e-05
Chromosome 5
114.90180
26
3.801744e-13
1.026471e-12
Chromosome 6
45.97560
26
0.00917934
1.457895e-02
Chromosome 7
1.94880
26
0.998329325823115
9.983293e-01
Chromosome 8
87.85480
26
1.227245e-08
2.548893e-08
Chromosome 9
1.68040
26
0.998329325823115
9.983293e-01
Chromosome 10
16.71380
26
0.9174746
9.983293e-01
Chromosome 11
1.68040
26
0.998329325823115
9.983293e-01
Chromosome 12
66.04280
26
2.455075e-05
4.419135e-05
Chromosome 13
16.71380
26
0.9174746
9.983293e-01
Chromosome 14
117.04940
26
1.614926e-13
4.844778e-13
Chromosome 15
15.90860
26
0.9383771
9.983293e-01
Chromosome 16
66.04280
26
2.455075e-05
4.419135e-05
Chromosome 17
0.00240
26
0.998329325823115
9.983293e-01
Chromosome 18
0.00240
26
0.998329325823115
9.983293e-01
Chromosome 19
147.98900
26
4.899984e-19
2.204993e-18
Chromosome 20
0.00240
26
0.998329325823115
9.983293e-01
Chromosome 21
87.85480
26
1.227245e-08
2.548893e-08
Chromosome 22
89.73400
26
6.137819e-09
1.506556e-08
Chromosome 23
117.04940
26
1.614926e-13
4.844778e-13
Chromosome 24
117.04940
26
1.614926e-13
4.844778e-13
Chromosome 25
147.98900
26
4.899984e-19
2.204993e-18
Chromosome 26
29.53260
26
0.2874251
4.311376e-01
Chi-squared (χ2) test: Which of the 20 blood parameters traits are over-represented in the QTLdb
Traits
Total χ2
df
p-values
FDR *
Size of χ2
Blood albumin level
14.80602
19
0.734844
8.645224e-01
Blood alpha-1 globulin level
9.64287
19
0.9612123
9.832407e-01
Blood beta-globulin level
21.66473
19
0.3012584
5.020973e-01
Blood gamma-globulin level
15.55557
19
0.6866936
8.583670e-01
Blood globulin level
15.55557
19
0.6866936
8.583670e-01
Blood total protein level
37.36928
19
0.007132053
2.037729e-02
Change in hematocrit
41.65773
19
0.001970851
1.281021e-02
Cholesterol level (total)
8.31251
19
0.9832407
9.832407e-01
Cortisol level
148.00001
19
5.323803e-22
1.064761e-20
Hematocrit
38.09454
19
0.005772484
1.924161e-02
Hemoglobin
28.47662
19
0.07467574
1.541440e-01
Mean corpuscular hemoglobin concentration
40.80485
19
0.002562042
1.281021e-02
Mean corpuscular hemoglobin content
19.3798
19
0.4327266
6.657332e-01
Mean corpuscular volume
27.53942
19
0.09270225
1.685495e-01
Pepsinogen level
38.92058
19
0.004522727
1.809091e-02
Platelet count
45.02896
19
0.0006790268
6.790268e-03
Red blood cell count
18.83528
19
0.467448
6.677829e-01
Red blood cell distribution width
28.34157
19
0.07707202
1.541440e-01
Sodium level
28.80001
19
0.06919664
1.541440e-01
creatinine level
9.64287
19
0.9612123
9.832407e-01
Correlations found between some of these traits for your reference
No correlation data found on these traits
Overall Test
Data
Chi'Square Test
Fisher's Exact Test
Number of chrom.:
27
χ2
=
3375.838000
Number of traits:
20
df
=
494
Number of QTLs:
298
p-value
=
0
FOOT NOTE: * : FDR is short for "false
discovery rate", representing the expected proportion of type I errors. A type I
error is where you incorrectly reject the null hypothesis, i.e. you get a false
positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where
V = Number of Type I errors (false positives); R = Number of rejected hypotheses.
Benjamini–Hochberg procedure is a practical way to estimate FDR.
Running...
