Release 56
(Apr 24, 2025)

This linkage-map based data has been obsolete
(see Release notes 51, 52, 53). Information
provided here is only for retrospective online
support of publications that used this data.

QTL 1833 Description:

 Trait Information
Trait name: Marek's disease susceptibility Vertebrate Trait Ontology: n/a
Reported name: Marek's disease-related traits Product Trait Ontology: n/a
Symbol: MD Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:1
QTL Peak Location:387 (cM)
QTL Span:386-387 (cM)
133.6-133.9 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":UMA1.019
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:Microsatellites
Analysis type:QTL
Model tested:n/a
Test base:Chromosome-wise
Threshold significance level:n/a
P_values<0.05
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

User inputs on QTL #1833
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  •  QTL Experiment in Brief
    Animals:A resource population of 272 F2 White Leghorn chickens was generated by intermating the inbred lines 6_3 (MD resistant) and 7_2 (MD susceptible).
     Breeds associated:
    n/a
    Design:All animals were necropsied to score for MD tumors in various nerves (vagus, sciatic, brachial) and visceral tissues. Any animal with a tumor was scored as having MD or diseased.
    Analysis:Microsatellite markers were chosen from the East Lansing, Compton, and Wageningen genetic maps. All 272 F2 birds were genotyped using the flanking markers within the MD QTL regions that were reported or for any marker that exhibited suggestive association
    Software:Genescan 2.1 Software
    Notes:MD = Marek's disease SG = selective genotyping
    Links:Edit

     Reference
    Authors:Yonash N, Bacon LD, Witter RL, Cheng HH.
    Affiliation:USDA-ARS, Avian Disease and Oncology Laboratory, East Lansing, MI 48823, USA.
    Title:High resolution mapping and identification of new quantitative trait loci (QTL)affecting susceptibility to Marek's disease.
    Journal:Animal Genetics, 1999, 30(2):126-35
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #10376303
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  • Cite this Data:

    Animal QTLdb: QTL1833 was published in 1999, and was curated into QTLdb on 2006-08-07. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:1833

     

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