Selection for increased resistance to Salmonella colonisation and excretioncould reduce the risk of foodborne Salmonella infection. In order to identifypotential loci affecting resistance, differences in resistance were identifiedbetween the N and 6(1) inbred lines and two QTL research performed. In an F2cross, the animals were inoculated at one week of age with Salmonellaenteritidis and cloacal swabs were carried out 4 and 5 wk post inoculation(thereafter called CSW4F2 and CSW4F2) and caecal contamination (CAECF2) wasassessed 1 week later. The animals from the (N x 6(1)) x N backcross wereinoculated at six weeks of age with Salmonella typhimurium and cloacal swabswere studied from wk 1 to 4 (thereafter called CSW1BC to CSW4BC). A total of 33F2 and 46 backcross progeny were selectively genotyped for 103 and 135microsatellite markers respectively. The analysis used least-squares-based andnon-parametric interval mapping. Two genome-wise significant QTL were observedon Chromosome 1 for CSW2BC and on Chromosome 2 for CSW4F2, and four suggestiveQTL for CSW5F2 on Chromosome 2, for CSW5F2 and CSW2BC on chromosome 5 and forCAECF2 on chromosome 16. These results suggest new regions of interest and theputative role of SAL1.