| QTL Map Information |
|---|
| Chromosome: | 28 |
| QTL Peak Location: | 80.36 (cM) |
| QTL Span: | 80.36-80.36 (cM)
43.7-43.7 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs69404339 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | Comparison-wise |
| Threshold significance level: | Significant |
 |
P_values | 4.66E-5 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | TBC1D22A (TBC1 domain family, member 22A ) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Norwegian Standardbred trotters. |
| Breeds associated:
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| Design: | Animals were genotyped using the Illumina EquineSNP50 BeadChip and analyzed for osteochondrosis phenotypes. A total of 41,170 SNPs were used for analysis. |
| Analysis: | Chi-square test, logistic regression using the Cochran–Mantel–Haenszel (CMH) test, and mixed-model analysis were performed. |
| Software: | PLINK Version 1.07, R package |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Lykkjen S, Dolvik NI, McCue ME, Rendahl AK, Mickelson JR, Roed KH |
| Affiliation: | The Norwegian School of Veterinary Science, Department of Basic Sciences and Aquatic Medicine, Post-box 8146 Dep., N-0033 Oslo, Norway |
| Title: | Genome-wide association analysis of osteochondrosis of the tibiotarsal joint in Norwegian Standardbred trotters |
| Journal: | Animal Genetics, 2010, 41 (Suppl. 2):111–120 |
| Links: |
PubMed | Abstract | List all data
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