| QTL Map Information |
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| Chromosome: | 10 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
|
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | rs1138901655 |
| Peak: | |
| Lower, "Significant": | rs3432635216 |
| Lower, "Suggestive": | n/a |
| Marker type: | SIG of SEL |
| Analysis type: | Association |
| Model tested: | - |
| Test base: | Genome-wise |
| Threshold significance level: | Significant |
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P_values | <0.05 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | n/a |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
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| Animals: | Horses were from 10 breeds assigned to four degenerative suspensory ligament desmitis risk categories: control (Belgian, Icelandic, Shetland Pony, Welsh Pony); low risk (Lusitano, Arabian); medium risk (Standardbred, Thoroughbred, Quarter Horse) and high risk (Peruvian Horse). |
| Breeds associated:
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| Design: | Animals were genotyped using varying platforms. GWAS and selection signature analysis were performed for degenerative suspensory ligament desmitis. |
| Analysis: | A univariate linear mixed model was used for GWAS |
| Software: | PLINK v1.9, BGLR in R, |
| Notes: | |
| Links: | Edit |
| Reference |
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| Authors: | Momen M, Brounts SH, Binversie EE, Sample SJ, Rosa GJM, Davis BW, Muir P |
| Affiliation: | Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA |
| Title: | Selection signature analyses and genome-wide association reveal genomic hotspot regions that reflect differences between breeds of horse with contrasting risk of degenerative suspensory ligament desmitis |
| Journal: | G3 (Genes | Genomics | Genetics), 2022, 12(10):jkac179 |
| Links: |
PubMed | Abstract | List all data
| Edit |
| Additional Information |
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| Comments: | high risk vs. control |
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