| QTL Map Information |
|---|
| Chromosome: | 6 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
32.1-32.1 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs68637327 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | - |
| Test base: | Genome-wise |
| Threshold significance level: | Significant |
 |
P_values | <0.05 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | TSPAN9 (tetraspanin 9) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Samples were from several sources, including horses in active EHM outbreaks, horses that had survived previous outbreaks, and banked samples stored in the context of a previous outbreak or experimental infection. |
| Breeds associated:
n/a
|
| Design: | Samples were genotyped using the Illumina SNP50 or SNP70 arrays and GWAS was performed for development of neurologic disease in animals infected with EHV-1. A total of 37,064 SNPs were used for analysis. |
| Analysis: | A mixed linear model was used. |
| Software: | GEMMA, Haploview 4.2, GCTA |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Brosnahan M M, Al Abri M A, Brooks S A, Antczak D F, Osterrieder N |
| Affiliation: | Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, United States; College of Veterinary Medicine, Midwestern University, Glendale, AZ 85308, United States |
| Title: | Genome-wide association study of equine herpesvirus type 1-induced myeloencephalopathy identifies a significant single nucleotide polymorphism in a platelet-related gene |
| Journal: | Veterinary journal (London, England : 1997), 2019, 245: 49-54 |
| Links: |
PubMed | Abstract | List all data
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