| QTL Map Information |
|---|
| Chromosome: | 21 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
0.2-0.2 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs1148949845 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | n/a |
| Test base: | n/a |
| Threshold significance level: | Significant |
 |
P_values | <0.01 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | n/a |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were NAD/EDM affected and control Quarter Horses. |
| Breeds associated:
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| Design: | Animals were subjected to whole-genome sequencing, and association analysis was performed for equine neuroaxonal dystrophy/degenerative myeloencephalopathy. |
| Analysis: | A case-control study was used. Genetic variants were identified in 28 candidate genes and subsequently used in a follow-up study in a validation population. |
| Software: | SAMtools, GATK HaplotypeCaller, PLINK |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Ma Y, Peng S, Donnelly CG, Ghosh S, Miller AD, Woolard K, Finno CJ |
| Affiliation: | Department of Population Health and Reproduction, School of Veterinary Medicine, University of California-Davis, Davis, California 95616, USA |
| Title: | Genetic polymorphisms in vitamin E transport genes as determinants for risk of equine neuroaxonal dystrophy |
| Journal: | Journal of veterinary internal medicine, 2024, 38(1):417-423 |
| Links: |
PubMed | Abstract | List all data
| Edit |
| Additional Information |
|---|
| Comments: | Whole-genome sequencing |
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