Release 56
(Apr 24, 2025)

QTL 193154 Description:

 Trait Information
Trait name: Equine neuroaxonal dystrophy/degenerative myeloencephalopathy Vertebrate Trait Ontology: n/a
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: NADEDM Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:7
QTL Peak Location:n/a
QTL Span:n/a
2.1-2.1 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs1149744811
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Experiment-wise
Threshold significance level:Suggestive
FDR<0.10
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Quarter Horses.
     Breeds associated:
    Design:Animals were genotyped using the Affymetrix Axiom Equine Genotyping Array and analyzed for equine neuroaxonal dystrophy incidence. A total of 488,210 SNPs were used for analysis.
    Analysis:A genome-wide efficient mixed-model analysis (GEMMA) was performed.
    Software:PLINK
    Notes: 
    Links:Edit

     Reference
    Authors:Hales EN, Esparza C, Peng S, Dahlgren AR, Peterson JM, Miller AD, Finno CJ
    Affiliation:Department of Population, Health and Reproduction, University of California, Davis School of Veterinary Medicine, Davis, CA 95616, USA.
    Title:Genome-Wide Association Study and Subsequent Exclusion of ATCAY as a Candidate Gene Involved in Equine Neuroaxonal Dystrophy Using Two Animal Models.
    Journal:Genes, 2020, 11(1):E82
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #31936863
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  • Cite this Data:

    Animal QTLdb: QTL193154 was published in 2020, and was curated into QTLdb on 2020-02-05. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:193154

     

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