Release 56
(Apr 24, 2025)

QTL 180500 Description:

 Trait Information
Trait name: Bone fracture Vertebrate Trait Ontology: Bone strength trait
Reported name: carpus fracture Product Trait Ontology: n/a
Symbol: BFSUS Clinical Measurement Ontology: n/a
 QTL Map Information
Chromosome:18
QTL Peak Location:123.07 (cM)
QTL Span:123.07-123.07 (cM)
66.0-66.0 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs69125077
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Genome-wise
Threshold significance level:Significant
P_values<0.0125
Dominance effect:n/a
Additive effect:n/a
Associated Gene:MSTN (myostatin)
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Japanese Thoroughbred racehorses.
     Breeds associated:
    Design:Animals were genotyped for four candidate SNPs in the MSTN gene and analyzed for fracture history.
    Analysis:Case/control association analysis was carried out using chi-squared test.
    Software:SPSS
    Notes: 
    Links:Edit

     Reference
    Authors:Tozaki T, Kusano K, Ishikawa Y, Kushiro A, Nomura M, Kikuchi M, Kakoi H, Hirota K, Miyake T, Hill E W, Nagata S
    Affiliation:Genetic Analysis Department, Laboratory of Racing Chemistry, 1731-2 Tsurutamachi, Utsunomiya, Tochigi, 320-0851, Japan
    Title:A candidate-SNP retrospective cohort study for fracture risk in Japanese Thoroughbred racehorses
    Journal:Animal genetics, 2020, 51(1):43-50
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:carpus
    User inputs on reference #31612520
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  • Cite this Data:

    Animal QTLdb: QTL180500 was published in 2020, and was curated into QTLdb on 2019-11-01. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:180500

     

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