Release 56
(Apr 24, 2025)

QTL 106322 Description:

 Trait Information
Trait name: Recurrent airway obstruction Vertebrate Trait Ontology: n/a
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: HEAVES Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:5
QTL Peak Location:54.52 (cM)
QTL Span:54.29-54.74 (cM)
5.6-5.7 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:CNV
Analysis type:Association
Model tested:Mendelian
Test base:Genome-wise
Threshold significance level:Suggestive
P_values0.06
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were severely RAO-affected and healthy control horses of various breeds.
     Breeds associated:
    n/a
    Design:Cases and controls were used for CNV discovery by array comparative genomic hybridization (aCGH). Follow-up tests were performed using qPCR and RAO-exclusive variants were subjected to further analysis.
    Analysis:Novel CNVs were analyzed for genotype-phenotype association using the parametric Student's t-test
    Software:R software
    Notes: 
    Links:Edit

     Reference
    Authors:Ghosh S, Das P J, McQueen C M, Gerber V, Swiderski C E, Lavoie J-P, Chowdhary B P, Raudsepp T
    Affiliation:Department of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX, 77843, USA
    Title:Analysis of genomic copy number variation in equine recurrent airway obstruction (heaves)
    Journal:Animal genetics, 2016, 47(3): 334-44
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #26932307
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  • Cite this Data:

    Animal QTLdb: QTL106322 was published in 2016, and was curated into QTLdb on 2016-08-10. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:106322

     

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