Release 56
(Apr 24, 2025)

QTL 57462 Description:

 Trait Information
Trait name: M. paratuberculosis susceptibility Vertebrate Trait Ontology: n/a
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: MPARA Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:1
QTL Peak Location:131.30 (cM)
QTL Span:131.30-131.30 (cM)
136.0-136.0 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs43255862
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Comparison-wise
Threshold significance level:Significant
P_values1.93E-5
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were German Holstein cattle.
     Breeds associated:
    Design:Animals were genotyped using the Illumina Bovine SNP50 BeadChip v1 or v2 and analyzed for MAP incidence using fecal culture and four commercial ELISA kits. A total of 40,079 SNPs were used for analysis.
    Analysis:GWAS was performed using the 'qtscore' function for a binary trait.
    Software:GenABEL in R
    Notes:Chromosome assignment for significant markers differs from positions reported in dbSNP; dbSNP locations were used.
    Links:Edit

     Reference
    Authors:Küpper J, Brandt H, Donat K, Erhardt G
    Affiliation:Institut für Tierzucht und Haustiergenetik,Justus-Liebig-Universität,Ludwigstraße 21b,35390 Gießen,Germany
    Title:Phenotype definition is a main point in genome-wide association studies for bovine Mycobacterium avium ssp. paratuberculosis infection status
    Journal:Animal : an international journal of animal bioscience, 2014, 8(10): 1586-93
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:Animals positive in all four ELISA tests
    User inputs on reference #25231280
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  • Cite this Data:

    Animal QTLdb: QTL57462 was published in 2014, and was curated into QTLdb on 2015-08-19. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:57462

     

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