Release 56
(Apr 24, 2025)

QTL 31754 Description:

 Trait Information
Trait name: Prolactin level Vertebrate Trait Ontology: Blood prolactin amount
Reported name: Prolactin level Product Trait Ontology: n/a
Symbol: PROLAC Clinical Measurement Ontology: Serum prolactin level
 QTL Map Information
Chromosome:14
QTL Peak Location:32.10 (cM)
QTL Span:32.10-32.10 (cM)
22.9-22.9 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs42646708
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:n/a
Threshold significance level:Significant
P_values0.022
Dominance effect:n/a
Additive effect:n/a
Associated Gene:XKR4 (XK, Kell blood group complex subunit-related family, member 4)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were mixed-breed (Angus, Simmental, and Charolais) cattle.
     Breeds associated:
    Design:Animals were genotyped for three SNPs in XKR4 and analyzed for serum prolactin level as an indicator of toxicosis incidence.
    Analysis:PROC MIXED was used.
    Software:SAS, R software
    Notes: 
    Links:Edit

     Reference
    Authors:Bastin B C, Houser A, Bagley C P, Ely K M, Payton R R, Saxton A M, Schrick F N, Waller J C, Kojima C J
    Affiliation:Department of Animal Science, University of Tennessee, Knoxville, TN, 37996, USA
    Title:A polymorphism in XKR4 is significantly associated with serum prolactin concentrations in beef cows grazing tall fescue
    Journal:Animal genetics, 2014, 45(3): 439-41
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #24666329
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  • Cite this Data:

    Animal QTLdb: QTL31754 was published in 2014, and was curated into QTLdb on 2014-11-19. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:31754

     

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