Release 56
(Apr 24, 2025)

QTL 28691 Description:

 Trait Information
Trait name: Bovine tuberculosis susceptibility Vertebrate Trait Ontology: n/a
Reported name: Bovine tuberculosis susceptibility Product Trait Ontology: n/a
Symbol: BTBS Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:13
QTL Peak Location:85.61 (cM)
QTL Span:85.69-85.72 (cM)
71.1-71.1 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":rs109910368
Peak:
Lower, "Significant":rs137562332
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:QTL
Model tested:Mendelian
Test base:Comparison-wise
Threshold significance level:Significant
F_Stat23.28
P_values1.6E-6
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Holstein-Friesian cattle.
     Breeds associated:
    Design:Animals were genotyped using the Illumina BovineHD BeadChip and analyzed for bovine tuberculosis incidence. A total of 617,010 SNPs were used for association analysis.
    Analysis:The genome-wide rapid association using mixed model and regression approach was used.
    Software:GenABEL in R, Haploview, ASReml
    Notes: 
    Links:Edit

     Reference
    Authors:Bermingham ML, Bishop SC, Woolliams JA, Pong-Wong R, Allen AR, McBride SH, Ryder JJ, Wright DM, Skuce RA, McDowell SWJ, Glass EJ
    Affiliation:The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK
    Title:Genome-wide association study identifies novel loci associated with resistance to bovine tuberculosis
    Journal:Heredity, 2014, 112(5): 543-51
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #24496092
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  • Cite this Data:

    Animal QTLdb: QTL28691 was published in 2014, and was curated into QTLdb on 2014-08-13. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:28691

     

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