| QTL Map Information |
|---|
| Chromosome: | 7 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
90.4-90.4 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs29011503 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | n/a |
| Test base: | Comparison-wise |
| Threshold significance level: | Significant |
 |
P_values | 7.11E-5 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | ADGRV1 (adhesion G protein-coupled receptor V1) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were first-lactation Holstein Friesian cows. |
| Breeds associated:
|
| Design: | Animals were genotyped using the Illumina BovineSNP50 v2 BeadChip or the Bovine Eurogenomics 10k chip (data imputed to 50K), and GWAS was performed for claw disorders. A total of 44,046 SNPs were used for analysis. |
| Analysis: | GWAS was performed in a case-control design by a applying a single-SNP linear mixed model and using the mlma-loco "leaving one chromosome out" option in GCTA. |
| Software: | PLINK, GCTA |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Sölzer N, May K, Yin T, König S |
| Affiliation: | Institute of Animal Breeding and Genetics, Justus-Liebig-University Giessen, 35390 Giessen, Germany |
| Title: | Genomic analyses of claw disorders in Holstein cows: Genetic parameters, trait associations, and genome-wide associations considering interactions of SNP and heat stress |
| Journal: | Journal of dairy science, 2022, 105(10): 8218-8236 |
| Links: |
PubMed | Abstract | List all data
| Edit |
| Additional Information |
|---|
| Comments: | SNP x heat stress interaction |
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