Release 56
(Apr 24, 2025)

QTL 25191 Description:

 Trait Information
Trait name: Milk fat percentage Vertebrate Trait Ontology: Milk fat amount
Reported name: Milk fat percentage Product Trait Ontology: Milk fat content
Symbol: FP Clinical Measurement Ontology: Milk fat percentage
 QTL Map Information
Chromosome:6
QTL Peak Location:63.3 (cM)
QTL Span:30.22-30.42 (cM)
26.5-26.7 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:Association
Model tested:Mendelian
Test base:Comparison-wise
Threshold significance level:Significant
F_Stat5.18
P_values0.0231
Dominance effect:n/a
Additive effect:n/a
Associated Gene:UGDH (UDP-glucose 6-dehydrogenase)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Chinese Holstein cows.
     Breeds associated:
    Design:Animals were genotyped for 64 SNPs in a QTL region on BTA6 and analyzed for milk production traits. UGDH was determined to be the most plausible candidate gene (10 SNPs used for association analysis).
    Analysis:The MIXED procedure was used.
    Software:SAS, Haploview
    Notes: 
    Links:Edit

     Reference
    Authors:Xu Q, Mei G, Sun D, Zhang Q, Zhang Y, Yin C, Chen H, Ding X, Liu J
    Affiliation:Department of Animal Genetics and Breeding, College of Animal Science and Technology, Key Laboratory of Animal Genetics and Breeding of Ministry of Agriculture, National Engineering Laboratory for Animal Breeding, China Agricultural
    Title:Detection of genetic association and functional polymorphisms of UGDH affecting milk production trait in Chinese Holstein cattle
    Journal:BMC genomics, 2012, 13: 590
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #23122059
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  • Cite this Data:

    Animal QTLdb: QTL25191 was published in 2012, and was curated into QTLdb on 2014-05-13. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:25191

     

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