| QTL Map Information |
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| Chromosome: | 6 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
87.0-87.0 (Mbp) |
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Upper, "Suggestive": | n/a |
| Upper, "Significant": | rs460431378 |
| Peak: | rs110813063 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | CNV |
| Analysis type: | QTL |
| Model tested: | n/a |
| Test base: | Chromosome-wise |
| Threshold significance level: | Significant |
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P_values | 0.00000000000000 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | GC (group-specific component (vitamin D binding protein)) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Dutch Holstein-Friesian cattle. |
| Breeds associated:
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| Design: | Animals were genotyped using a low-density array, with data imputed to sequence level, and association analysis and fine-mapping were performed for clinical mastitis incidence on BTA6. |
| Analysis: | Association mapping was performed using a linear mixed model. CNV discovery, selection signature analysis, and eQTL mapping were also carried out. |
| Software: | GCTA, Beagle 4, SAMtools, LINKPHASE3, SVTyper, Duphold |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Lee YL, Takeda H, Costa Monteiro Moreira G, Karim L, Mullaart E, Coppieters W; GplusE consortium, Appeltant R, Veerkamp RF, Groenen MAM, Georges M, Bosse M, Druet T, Bouwman AC, Charlier C |
| Affiliation: | Wageningen University & Research, Animal Breeding and Genomics, Wageningen, the Netherlands |
| Title: | A 12 kb multi-allelic copy number variation encompassing a GC gene enhancer is associated with mastitis resistance in dairy cattle |
| Journal: | PLoS genetics, 2021, 17(7): e1009331 |
| Links: |
PubMed | Abstract | List all data
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