Release 56
(Apr 24, 2025)

QTL 221807 Description:

 Trait Information
Trait name: M. paratuberculosis susceptibility Vertebrate Trait Ontology: n/a
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: MPARA Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:8
QTL Peak Location:n/a
QTL Span:n/a
107.1-107.1 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs8193046
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:n/a
Test base:n/a
Threshold significance level:Significant
P_values0.0092
Dominance effect:n/a
Additive effect:n/a
Associated Gene:TLR4 (toll-like receptor 4)
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Sahiwal, Tharparkar, Gir, Kankrej, and Frieswal (Holstein Friesian x Sahiwal) crossbred.
     Breeds associated:
    Design:Animals were genotyped for a total of seven SNPs in the CLEC7A, CD209, and TLR4 genes and analyzed for SNP association with paratuberculosis susceptibility.
    Analysis:A univariate logistic regression model was used.
    Software:SAS 9.3
    Notes: 
    Links:Edit

     Reference
    Authors:Gopi B, Singh RV, Kumar S, Kumar S, Chauhan A, Kumar A, Singh SV
    Affiliation:Division of Animal Genetics, ICAR-Indian Veterinary Research Institute, Izatnagar 243 122, India
    Title:Single-nucleotide polymorphisms in CLEC7A, CD209 and TLR4 gene and their association with susceptibility to paratuberculosis in Indian cattle
    Journal:Journal of genetics, 2020, 99:14
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #32366737
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  • Cite this Data:

    Animal QTLdb: QTL221807 was published in 2020, and was curated into QTLdb on 2021-05-17. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:221807

     

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