| QTL Map Information |
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| Chromosome: | 23 |
| QTL Peak Location: | n/a |
| QTL Span: | n/a
19.3-19.3 (Mbp) |
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Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs481146807 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | n/a |
| Test base: | Experiment-wise |
| Threshold significance level: | Significant |
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FDR | 3.93E-03 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | n/a |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
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| QTL Experiment in Brief |
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| Animals: | Animals were 983 Spanish Holstein cows. |
| Breeds associated:
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| Design: | Animals were analysed for Mycobacterium avium subspecies paratuberculosis (MAP)-specific humoral response and/or culture/PCR for MAP detection in gut tissues. Animals were genotyped using the Bovine MD SNP50 Bead Chip. Data were imputed to HD, then to WGS data and SNP association with bovine paratuberculosis infection was analyzed. A total of 33,774,937 autosomal SNPs were used for analysis. |
| Analysis: | Linear mixed models were used. |
| Software: | Eagle, minimac4, GCTA |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Canive M, González-Recio O, Fernandez A, Vázquez P, Badia-Bringué G, Lavín JL, Garrido JM, Juste RA, Alonso-Hearn M |
| Affiliation: | Department of Animal Health, NEIKER- Basque Research and technology Alliance (BRTA), Derio, Bizkaia, Spain |
| Title: | Identification of loci associated with susceptibility to Mycobacterium avium subsp. paratuberculosis infection in Holstein dairy cattle using combinations of diagnostic tests and imputed whole-genome sequence data |
| Journal: | PLOS One, 2021, 16(8): e0256091. |
| Links: |
PubMed | Abstract | List all data
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