| QTL Map Information |
|---|
| Chromosome: | 6 |
| QTL Peak Location: | 64.46 (cM) |
| QTL Span: | 64.46-64.46 (cM)
58.4-58.4 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs474302732 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | Genome-wise |
| Threshold significance level: | Significant |
 |
P_values | <0.05 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | WDR19 (WD repeat domain 19) |
| Cis/Trans acting type: |  |
| Links:
Edit |
Map view
|
| Extended information: |
|---|
| (none) |
User inputs on QTL #211753
Add your annotations
Add your comments
Report problems
|
| QTL Experiment in Brief |
|---|
| Animals: | Animals were Brown Swiss bulls. |
| Breeds associated:
|
| Design: | Animals were genotyped using the Ilumina BovineSNP50 (with data imputed to HD) or BovineHD BeadChip and analyzed for semen quality traits. A total of 607,511 SNPs were used for analysis. |
| Analysis: | Haplotype-based association testing was implemented using a sliding window-based approach and a linear model. Candidate SNPs were identified and genotyped. |
| Software: | PLINK, Minimac3, Beagle, Eagle, R software |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Hiltpold M, Niu G, Kadri NK, Crysnanto D, Fang ZH, Spengeler M, Schmitz-Hsu F, Fuerst C, Schwarzenbacher H, Seefried FR, Seehusen F, Witschi U, Schnieke A, Fries R, Bollwein H, Flisikowski K, Pausch H |
| Affiliation: | Animal Genomics, ETH Zürich, Lindau, Switzerland |
| Title: | Activation of cryptic splicing in bovine WDR19 is associated with reduced semen quality and male fertility |
| Journal: | PLoS genetics, 2020, 16(5): e1008804 |
| Links: |
PubMed | Abstract | List all data
| Edit |
User inputs on reference #32407316
Add your comments
Note similar findings
Note contradictions
|
