Release 56
(Apr 24, 2025)

QTL 20538 Description:

 Trait Information
Trait name: Degree of spotting Vertebrate Trait Ontology: Coat/hair pigmentation trait
Reported name: Degree of Spotting Product Trait Ontology: n/a
Symbol: DS Clinical Measurement Ontology: n/a
 QTL Map Information
Chromosome:22
QTL Peak Location:41.9 (cM)
QTL Span:32.58-32.78 (cM)
22.5-22.6 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:Association
Model tested:Mendelian
Test base:n/a
Threshold significance level:Significant
P_values8.2E-12
Dominance effect:n/a
Additive effect:n/a
Associated Gene:MITF (microphthalmia-associated transcription factor)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Italian Holstein, Italian Simmental, Italian Brown, and Reggiana cattle.
     Breeds associated:
    Design:Animals were genotyped for two SNPs in MITF and analyzed for degree of spotting.
    Analysis:Permutation testing was performed.
    Software:PHASE
    Notes: 
    Links:Edit

     Reference
    Authors:Fontanesi L, Scotti E, Russo V
    Affiliation:DIPROVAL, Sezione di Allevamenti Zootecnici, Faculty of Agriculture, University of Bologna, Italy.
    Title:Haplotype variability in the bovine MITF gene and association with piebaldism in Holstein and Simmental cattle breeds.
    Journal:Animal genetics, 2012, 43 (3): 250-6
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:g.32386957A>T
    User inputs on reference #22486495
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  • Cite this Data:

    Animal QTLdb: QTL20538 was published in 2012, and was curated into QTLdb on 2013-04-24. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:20538

     

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