Release 56
(Apr 24, 2025)

QTL 194888 Description:

 Trait Information
Trait name: Dopamine level Vertebrate Trait Ontology: n/a
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: DOPA Clinical Measurement Ontology: Blood dopamine level
 QTL Map Information
Chromosome:12
QTL Peak Location:101.01 (cM)
QTL Span:101.01-101.01 (cM)
76.9-76.9 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs718072819
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Comparison-wise
Threshold significance level:Significant
P_values3.83E-07
Dominance effect:n/a
Additive effect:n/a
Associated Gene:PCCA (propionyl CoA carboxylase, alpha polypeptide)
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Brahman and Yunling cattle.
     Breeds associated:
    Design:GWAS was performed for serum concentration of five neurotransmitters (serotonin, dopamine, cortisol, glutamate, and ACTH). A total of 12,983,056 SNPs were used for analysis.
    Analysis:Mixed linear models.
    Software:GEMMA
    Notes: 
    Links:Edit

     Reference
    Authors:Chen Q, Qu K, Ma Z, Zhan J, Zhang F, Shen J, Ning Q, Jia P, Zhang J, Chen N, Chen H, Huang B, Lei C
    Affiliation:Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, China
    Title:Genome-Wide Association Study Identifies Genomic Loci Associated With Neurotransmitter Concentration in Cattle
    Journal:Frontiers in genetics, 2020, 11: 139
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #32292413
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  • Cite this Data:

    Animal QTLdb: QTL194888 was published in 2020, and was curated into QTLdb on 2020-05-06. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:194888

     

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