QTL Map Information |
Chromosome: | 17 |
QTL Peak Location: | 5.2 (cM) |
QTL Span: | 5.12-5.41 (cM) 3.9-4.1 (Mbp) |
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Upper, "Suggestive": | n/a |
Upper, "Significant": | n/a |
Peak: | |
Lower, "Significant": | n/a |
Lower, "Suggestive": | n/a |
Marker type: | |
Analysis type: | Association |
Model tested: | Mendelian |
Test base: | Experiment-wise |
Threshold significance level: | Significant |
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P_values | <0.05 | Dominance effect: | n/a |
Additive effect: | n/a |
Associated Gene: | TLR2 (toll-like receptor 2) |
Cis/Trans acting type: |  |
Links:
NCBI GeneDB | Edit |
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Extended information: |
(none) |
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QTL Experiment in Brief |
Animals: | Animals were Holstein-Friesian cattle. |
Breeds associated:
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Design: | Animals were genotyped for 24 SNP in TLR1, TLR2, and TLR4 and analyzed for MAP infection status. |
Analysis: | Association analysis was carried out under five different genetic models simultaneously: codominant, dominant, recessive, overdominant, and log-additive. |
Software: | SPSS, R, Haploview |
Notes: | |
Links: | Edit |
Reference |
Authors: | Ruiz-Larranaga O, Manzano C, Iriondo M, Garrido JM, Molina E, Vazquez P, Juste RA, Estonba A |
Affiliation: | Genetics, Physical Anthropology and Animal Physiology Department, University of the Basque Country, UPV/EHU, Sarriena s/n, 48940 Leioa, Bizkaia, Spain |
Title: | Genetic variation of toll-like receptor genes and infection by Mycobacterium avium ssp. paratuberculosis in Holstein-Friesian cattle |
Journal: | J Dairy Sci, 2011, 94(7):3635-41 |
Links: |
PubMed | Abstract | List all data
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