| QTL Map Information |
|---|
| Chromosome: | 7 |
| QTL Peak Location: | 4.83 (cM) |
| QTL Span: | 4.83-4.83 (cM)
4.0-4.0 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs109959260 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | Experiment-wise |
| Threshold significance level: | Significant |
 |
P_values | 0.014 | | Dominance effect: | n/a |
| Additive effect: | -0.37 |
| Associated Gene: | TM6SF2 (transmembrane 6 superfamily member 2) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
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| Animals: | Animals were Canadian Holstein cows. |
| Breeds associated:
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| Design: | Based on candidate genes identified in a previous GWAS, targeted genotyping was carried out, in which animals were genotyped for 126 SNPs and analyzed for milk cholesterol content, milk yield, and milk fat yield. |
| Analysis: | Association analyses, using both additive and dominance effect models, were performed using a univariate single-SNP mixed linear model. |
| Software: | DMU |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Do D N, Schenkel F, Miglior F, Zhao X, Ibeagha-Awemu E M |
| Affiliation: | Agriculture and Agri-Food Canada, Sherbrooke Research and Development Centre, Sherbrooke, QC, J1M 0C8, Canada |
| Title: | Targeted genotyping to identify potential functional variants associated with cholesterol content in bovine milk |
| Journal: | Anim Genet, 2020, 51(2):200-209 |
| Links: |
PubMed | Abstract | List all data
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