| QTL Map Information |
|---|
| Chromosome: | 1 |
| QTL Peak Location: | 87.8 (cM) |
| QTL Span: | 76.503-99.15 (cM)
78.4-101.7 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | INRA128 |
| Peak: | |
| Lower, "Significant": | CSSM32 |
| Lower, "Suggestive": | n/a |
| Marker type: | Microsatellites |
| Analysis type: | QTL |
| Model tested: | n/a |
| Test base: | n/a |
| Threshold significance level: | n/a |
 |
F_Stat | 3.9 | | P_values | 0.0308 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | n/a |
| Cis/Trans acting type: |  |
| Links:
NCBI GeneDB | Edit |
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Four half-sib Holstein sire families with 360 cows, of which 268 were BSE affected and 92 BSE unaffected, were analyzed. Study animals contracted BSE from the environment during the United Kingdom's epidemic of the late 1980s and 1990s. |
| Breeds associated:
n/a
|
| Design: | Control animals and BSE cases were sampled at approximately the same time from the same farms and were sire matched and age matched; hence, we make the assumption that both sets of animals were exposed to the same level of infectious agent. |
| Analysis: | A panel of 173 microsatellite markers was used. Linear regression methods were used for QTL analysis of the binary data. |
| Software: | Cri-Map |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Zhang C, De Koning DJ, Hernandez-Sanchez J, Haley CS, Williams JL, Wiener P. |
| Affiliation: | Roslin Institute (Edinburgh), Roslin, Midlothian EH25 9PS, United Kingdom. |
| Title: | Mapping of multiple quantitative trait loci affecting bovine spongiformencephalopathy. |
| Journal: | Genetics, 2004, 167(4):1863-72. |
| Links: |
PubMed | Abstract | List all data
| Edit |
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