| QTL Map Information |
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| Chromosome: | 8 |
| QTL Peak Location: | 116.88 (cM) |
| QTL Span: | 116.88-116.88 (cM)
107.1-107.1 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs8193046 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | n/a |
| Threshold significance level: | Significant |
 |
P_values | 0.0005 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | TLR4 (toll-like receptor 4) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Indian cattle of various breeds: Sahiwal, Tharparker, Holstein Friesian, and crossbred. |
| Breeds associated:
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| Design: | Animals were genotyped for two SNPs in TLR2 and two SNPs in TLR4 and analyzed for MAP infection status. |
| Analysis: | Univariate analysis was performed for categorical variables using a Chi-square test on the distribution of allele and genotype frequencies between cases and controls. The relative risk of incidence amount the genotypes was analyzed using a logistic regression model. |
| Software: | SAS |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Kumar S, Kumar S, Singh RV, Chauhan A, Kumar A, Sulabh S, Bharati J, Singh SV |
| Affiliation: | Animal Health Division, ICAR- Central Institute for Research on Goats, Makhdoom, U.P., 281112, India |
| Title: | Genetic association of polymorphisms in bovine TLR2 and TLR4 genes with Mycobacterium avium subspecies paratuberculosis infection in Indian cattle population |
| Journal: | Veterinary research communications, 2019, 43(2):105-114 |
| Links: |
PubMed | Abstract | List all data
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