| QTL Map Information |
|---|
| Chromosome: | 1 |
| QTL Peak Location: | 66.41 (cM) |
| QTL Span: | 66.41-66.41 (cM)
69.1-69.1 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | rs475149733 |
| Peak: | rs208311936 |
| Lower, "Significant": | rs136956602 |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | QTL |
| Model tested: | Mendelian |
| Test base: | Genome-wise |
| Threshold significance level: | Significant |
 |
P_values | <0.05 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | UMPS (uridine monophosphate synthetase) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Nordic Holstein cattle. |
| Breeds associated:
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| Design: | Animals were genotyped using the Illumina BovineSNP50 BeadChip v1 or v2, with data imputed to whole-genome sequence, and analyzed for fertility index. A total of 15,551,021 SNPs were used for association analysis. |
| Analysis: | A conditional GWAS was performed using a method in which the data was reanalyzed after fitting only the lead SNP on a chromosome. |
| Software: | IMPUTE2, Minimac2, GCTA, PLINK |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Cai Z, Guldbrandtsen B, Lund MS, Sahana G |
| Affiliation: | Center for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, 8830, Tjele, Denmark |
| Title: | Prioritizing candidate genes for fertility in dairy cows using gene-based analysis, functional annotation and differential gene expression |
| Journal: | BMC genomics, 2019, 20(1): 255 |
| Links: |
PubMed | Abstract | List all data
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