| QTL Map Information |
|---|
| Chromosome: | 22 |
| QTL Peak Location: | 16.96 (cM) |
| QTL Span: | 16.96-16.96 (cM)
11.3-11.3 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs136542584 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | Comparison-wise |
| Threshold significance level: | Significant |
 |
P_values | 1.13E-14 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | n/a |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Chinese Holstein cows. |
| Breeds associated:
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| Design: | Animals were genotyped using either the Illumina BovineSNP50 BeadChip (imputed to HD) or the GeneSeek Genomic Profiler HD v2 chip and analyzed for M. paratuberculosis infection status. |
| Analysis: | Two approaches were used for GWAS: Genome-wide Rapid Association using Mixed model and Regression-Genomic Control (GRAMMAR-GC) and ROADTRIPS using RM test. |
| Software: | PLINK, Beagle, GenABEL in R, ROADTRIPS 2.0, GCTA |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Gao Y, Jiang J, Yang S, Cao J, Han B, Wang Y, Zhang Y, Yu Y, Zhang S, Zhang Q, Fang L, Cantrell B, Sun D |
| Affiliation: | Key Laboratory of Animal Genetics and Breeding of Ministry of Agriculture, National Engineering Laboratory of Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100193, China |
| Title: | Genome-wide association study of Mycobacterium avium subspecies Paratuberculosis infection in Chinese Holstein |
| Journal: | BMC genomics, 2018, 19(1): 972 |
| Links: |
PubMed | Abstract | List all data
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| Additional Information |
|---|
| Comments: | GRAMMAR-GC method |
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