Release 56
(Apr 24, 2025)

QTL 161598 Description:

 Trait Information
Trait name: Clinical mastitis Vertebrate Trait Ontology: n/a
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: CM Clinical Measurement Ontology: Disease incidence/prevalence measurement
 QTL Map Information
Chromosome:18
QTL Peak Location:57.29 (cM)
QTL Span:56.98-57.60 (cM)
43.5-44.0 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":rs41882316
Peak:rs464881101
Lower, "Significant":rs524490384
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:QTL
Model tested:Mendelian
Test base:Comparison-wise
Threshold significance level:Significant
P_values3.02E-18
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Nordic Holstein cattle.
     Breeds associated:
    Design:Animals were genotyped using the Illumina BovineSNP50 BeadChip, with data imputed to whole-genome sequence, and analyzed for resistance to clinical mastitis. A total of 15,552,968 SNPs were used for analysis.
    Analysis:A conditional GWAS was performed using a method in which the data was reanalyzed after fitting only the lead SNP on a chromosome.
    Software:IMPUTE2, Minimac2, GCTA, PLINK
    Notes: 
    Links:Edit

     Reference
    Authors:Cai Z, Guldbrandtsen B, Lund MS, Sahana G
    Affiliation:Center for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, 8830, Tjele, Denmark
    Title:Prioritizing candidate genes post-GWAS using multiple sources of data for mastitis resistance in dairy cattle
    Journal:BMC genomics, 2018, 19(1): 656
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  
    User inputs on reference #30189836
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  • Cite this Data:

    Animal QTLdb: QTL161598 was published in 2018, and was curated into QTLdb on 2018-10-11. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:161598

     

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