| QTL Map Information |
|---|
| Chromosome: | 7 |
| QTL Peak Location: | 17.10 (cM) |
| QTL Span: | 17.10-17.10 (cM)
14.2-14.2 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs378570750 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | Comparison-wise |
| Threshold significance level: | Significant |
 |
P_values | 3.4E-7 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | n/a |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Holstein and Jersey dairy cattle. |
| Breeds associated:
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| Design: | Animals were genotyped for 17 SNPs in the ITK gene and analyzed for incidence of MAP infection. An association analysis was also carried out using imputed full genome sequence on BTA 7 (Holsteins only). |
| Analysis: | GRAMMAR-GC was used to conduct GWAS analysis. A Bayes C threshold model was used to detect 1 Mb windows associated with trait variation. |
| Software: | FImpute, GenABEL in R, GenSel |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Sallam AM, Zare Y, Shook G, Collins M, Kirkpatrick BW |
| Affiliation: | Department of Animal Sciences/Department of Dairy Science, College of Agricultural and Life Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA |
| Title: | A positional candidate gene association analysis of susceptibility to paratuberculosis on bovine chromosome 7 |
| Journal: | Infection, genetics and evolution, 2018, 65: 163-169 |
| Links: |
PubMed | Abstract | List all data
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