| QTL Map Information |
|---|
| Chromosome: | 13 |
| QTL Peak Location: | 92.19 (cM) |
| QTL Span: | 91.45-92.92 (cM)
76.7-77.9 (Mbp) |
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Upper, "Suggestive": | n/a |
| Upper, "Significant": | rs136700820 |
| Peak: | rs41711041 |
| Lower, "Significant": | rs460902551 |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | QTL |
| Model tested: | Mendelian |
| Test base: | Genome-wise |
| Threshold significance level: | Significant |
 |
P_values | <0.05 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | PREX1 (phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1) |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
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| Animals: | Animals were Nordic Holstein cattle. |
| Breeds associated:
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| Design: | Animals were genotyped using the Illumina Bovine SNP50 BeadChip, with data imputed to whole-genome sequence, and analyzed for milk yield traits. A total of 15,355,402 SNPs were used for analysis. |
| Analysis: | A conditional GWAS was performed using a method in which the data was reanalyzed after fitting only the lead SNP on a chromosome. |
| Software: | IMPUTE2, Minimac2, Beagle, GCTA |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Cai Z, Guldbrandtsen B, Lund MS, Sahana G |
| Affiliation: | Center for Quantitative Genetics and Genomics, Department of Molecular Biology and Genetics, Aarhus University, 8830, Tjele, Denmark |
| Title: | Dissecting closely linked association signals in combination with the mammalian phenotype database can identify candidate genes in dairy cattle |
| Journal: | BMC genetics, 2018, 19(1): 30 |
| Links: |
PubMed | Abstract | List all data
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