Release 56
(Apr 24, 2025)

QTL 14693 Description:

 Trait Information
Trait name: M. paratuberculosis susceptibility Vertebrate Trait Ontology: n/a
Reported name: M. paratuberculosis susceptibility Product Trait Ontology: n/a
Symbol: MPARA Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:9
QTL Peak Location:35.13 (cM)
QTL Span:35.13-35.13 (cM)
1.5-1.5 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs43070062
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Comparison-wise
Threshold significance level:Significant
P_values1.7E-05
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Holstein cattle.
     Breeds associated:
    Design:Animals were genotyped for 55,074 SNPs on the BovineSNP50 SNP chip and analyzed for tissue and fecal presence of Mycobacterium avium ssp. paratuberculosis.
    Analysis:Standard 1-d.f. allelic, 1-d.f. dominance, 1-d.f. recessive and 2-d.f. (genotypic) tests of association with genotype between cases and controls were calculated. Cochran-Mantel-Haenszel tests were performed upon evidence of stratification.
    Software:R software, PLINK
    Notes: 
    Links:Edit

     Reference
    Authors:Settles M, Zanella R, McKay SD, Schnabel RD, Taylor JF, Whitlock R, Schukken Y, Van Kessel JS, Smith JM, Neibergs H
    Affiliation:Department of Animal Sciences, Washington State University, Pullman, WA 99164, USA.
    Title:A whole genome association analysis identifies loci associated with Mycobacterium avium subsp. paratuberculosis infection status in US holstein cattle
    Journal:Animal Genetics, 2009, 40(5):655-62
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:Fecal positive
    User inputs on reference #19422364
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  • Cite this Data:

    Animal QTLdb: QTL14693 was published in 2009, and was curated into QTLdb on 2011-11-21. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:14693

     

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