QTL Map Information |
Chromosome: | 25 |
QTL Peak Location: | 43.87 (cM) |
QTL Span: | 43.87-43.87 (cM) 27.9-27.9 (Mbp) |
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Upper, "Suggestive": | n/a |
Upper, "Significant": | n/a |
Peak: | rs801168123 |
Lower, "Significant": | n/a |
Lower, "Suggestive": | n/a |
Marker type: | SNP |
Analysis type: | Association |
Model tested: | Mendelian |
Test base: | Comparison-wise |
Threshold significance level: | Significant |
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P_values | 4.5E-9 | Dominance effect: | n/a |
Additive effect: | n/a |
Associated Gene: | n/a |
Cis/Trans acting type: |  |
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Extended information: |
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QTL Experiment in Brief |
Animals: | Animals were Braunvieh, Fleckvieh, and Holstein cattle. |
Breeds associated:
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Design: | Animals were genotyped using the Illumina BovineSNP50 or BovineHD BeadChip, with data imputed to sequence level, and analyzed for SNP association with milk fat and protein percentage. |
Analysis: | Association tests were carried out for each breed separately using a variance components-based approach. Meta-analysis of FP and PP across breeds was carried out using an inverse variance-based approach. |
Software: | SAMtools, Minimac, FImpute, Beagle, Eagle, PLINK, EMMAX |
Notes: | |
Links: | Edit |
Reference |
Authors: | Pausch H, Emmerling R, Gredler-Grandl B, Fries R, Daetwyler HD, Goddard ME |
Affiliation: | Faculty of Veterinary and Agricultural Sciences, University of Melbourne, Melbourne, VIC, 3010, Australia |
Title: | Meta-analysis of sequence-based association studies across three cattle breeds reveals 25 QTL for fat and protein percentages in milk at nucleotide resolution |
Journal: | BMC genomics, 2017, 18(1): 853 |
Links: |
PubMed | Abstract | List all data
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