| QTL Map Information |
|---|
| Chromosome: | 17 |
| QTL Peak Location: | 5.5 (cM) |
| QTL Span: | 5.22-5.42 (cM)
4.0-4.1 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | n/a |
| Threshold significance level: | Significant |
 |
P_values | 0.0096 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | TLR2 (toll-like receptor 2) |
| Cis/Trans acting type: |  |
| Links:
NCBI GeneDB | Edit |
Map view
|
| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Holstein-Friesian cattle. |
| Breeds associated:
|
| Design: | Animals were genotyped for five SNPs in TLR2 and analyzed for susceptibility to bovine paratuberculosis. |
| Analysis: | Analysis was carried out using Fisher exact tests with correction for multiple comparisons. |
| Software: | R software |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Koets A, Santema W, Mertens H, Oostenrijk D, Keestra M, Overdijk M, Labouriau R, Franken P, Frijters A, Nielen M, Rutten V |
| Affiliation: | Department of Infectious Diseases and Immunology, Immunology Division, Utrecht, The Netherlands. a.p.koets@uu.nl |
| Title: | Susceptibility to paratuberculosis infection in cattle is associated with single nucleotide polymorphisms in Toll-like receptor 2 which modulate immune responses against Mycobacterium avium subspecies paratuberculosis |
| Journal: | Prev Vet Med, 2010, 93(4): 305-15 |
| Links: |
PubMed | Abstract | List all data
| Edit |
| Additional Information |
|---|
| Comments: | SNP01 |
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