Release 56
(Apr 24, 2025)

QTL 13116 Description:

 Trait Information
Trait name: M. paratuberculosis susceptibility Vertebrate Trait Ontology: n/a
Reported name: M. paratuberculosis susceptibility Product Trait Ontology: n/a
Symbol: MPARA Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:15
QTL Peak Location:30 (cM)
QTL Span:19.00-19.20 (cM)
14.7-14.9 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:Association
Model tested:Mendelian
Test base:Experiment-wise
Threshold significance level:Significant
P_values<0.05
Dominance effect:0.82
Additive effect:-0.67
Associated Gene:IL10RA (interleukin 10 receptor, alpha)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were from commercial Holstein populations.
     Breeds associated:
    Design:Animals were genotyped for SNPs in five immune-related genes and analyzed for MAP infection status.
    Analysis:A logistic regression approach was used.
    Software:SAS
    Notes: 
    Links:Edit

     Reference
    Authors:Cerschoor CP, Pant SD, You Q, Schenkel FS, Kelton D, Karrow NA
    Affiliation:Centre for Genetic Improvement of LIvestock, Department of Animal and Poultry Science, University of Guelph, 50 Stone Rd East, Guelph, Ontario, N1G2W1, Canada; nkarrow@uoguelph.ca
    Title:Polymorphisms in the gene encoding bovine interleukin-10 receptor alpha are associated with Mycobacterium avium ssp. paratuberculosis infection status
    Journal:BMC genetics, 2010, 11:23
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:948G>A
    User inputs on reference #20398313
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  • Cite this Data:

    Animal QTLdb: QTL13116 was published in 2010, and was curated into QTLdb on 2010-10-08. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:13116

     

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