| QTL Map Information |
|---|
| Chromosome: | 23 |
| QTL Peak Location: | 49.84 (cM) |
| QTL Span: | 43.89-55.79 (cM)
30.2-38.4 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | rs109862194 |
| Peak: | |
| Lower, "Significant": | rs41588617 |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | QTL |
| Model tested: | Mendelian |
| Test base: | Genome-wise |
| Threshold significance level: | Significant |
 |
LikelihoodR | 15.98 | | P_values | <0.05 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | n/a |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
|---|
| Animals: | Animals were Holstein-Friesian cattle. |
| Breeds associated:
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| Design: | Animals were genotyped using the Illumina BovineSNP50 BeadChip and analyzed for bTB susceptibility traits. A total of 34,874 SNPs were used for analysis. |
| Analysis: | Regression analysis was used for GWAS. Regional heritability mapping and chromosome association analysis were also performed. |
| Software: | GenABEL in R, PLINK, Haploview, DISSECT |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Raphaka K, Matika O, Sánchez-Molano E, Mrode R, Coffey MP, Riggio V, Glass EJ, Woolliams JA, Bishop SC, Banos G |
| Affiliation: | Scotland's Rural College, The Roslin Institute Building, Easter Bush, Midlothian, EH25 9RG, Edinburgh, UK |
| Title: | Genomic regions underlying susceptibility to bovine tuberculosis in Holstein-Friesian cattle |
| Journal: | BMC genetics, 2017, 18(1): 27 |
| Links: |
PubMed | Abstract | List all data
| Edit |
| Additional Information |
|---|
| Comments: | Phenotype 2 plus non-reactors and inconclusive reactors with positive post-mortem exam results |
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