Release 56
(Apr 24, 2025)

QTL 130275 Description:

 Trait Information
Trait name: Bovine tuberculosis susceptibility Vertebrate Trait Ontology: n/a
Reported name: (n/a) Product Trait Ontology: n/a
Symbol: BTBS Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:2
QTL Peak Location:84.66 (cM)
QTL Span:84.66-84.66 (cM)
92.6-92.6 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:rs110986640
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:SNP
Analysis type:Association
Model tested:Mendelian
Test base:Genome-wise
Threshold significance level:Suggestive
P_values<1
Dominance effect:n/a
Additive effect:n/a
Associated Gene:n/a
Cis/Trans acting type:
Links:   Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Holstein-Friesian cattle.
     Breeds associated:
    Design:Animals were genotyped using the Illumina BovineSNP50 BeadChip and analyzed for bTB susceptibility traits. A total of 34,874 SNPs were used for analysis.
    Analysis:Regression analysis was used for GWAS. Regional heritability mapping and chromosome association analysis were also performed.
    Software:GenABEL in R, PLINK, Haploview, DISSECT
    Notes: 
    Links:Edit

     Reference
    Authors:Raphaka K, Matika O, Sánchez-Molano E, Mrode R, Coffey MP, Riggio V, Glass EJ, Woolliams JA, Bishop SC, Banos G
    Affiliation:Scotland's Rural College, The Roslin Institute Building, Easter Bush, Midlothian, EH25 9RG, Edinburgh, UK
    Title:Genomic regions underlying susceptibility to bovine tuberculosis in Holstein-Friesian cattle
    Journal:BMC genetics, 2017, 18(1): 27
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:Positive reactors to skin test with positive post-mortem result
    User inputs on reference #28335717
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  • Cite this Data:

    Animal QTLdb: QTL130275 was published in 2017, and was curated into QTLdb on 2017-05-17. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:130275

     

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