| QTL Map Information |
|---|
| Chromosome: | 19 |
| QTL Peak Location: | 110.99 (cM) |
| QTL Span: | 110.99-110.99 (cM)
61.1-61.1 (Mbp) |
 |
Upper, "Suggestive": | n/a |
| Upper, "Significant": | n/a |
| Peak: | rs41572967 |
| Lower, "Significant": | n/a |
| Lower, "Suggestive": | n/a |
| Marker type: | SNP |
| Analysis type: | Association |
| Model tested: | Mendelian |
| Test base: | Comparison-wise |
| Threshold significance level: | Significant |
 |
P_values | 4.83E-5 | | Dominance effect: | n/a |
| Additive effect: | n/a |
| Associated Gene: | n/a |
| Cis/Trans acting type: |  |
| Links:
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| Extended information: |
|---|
| (none) |
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| QTL Experiment in Brief |
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| Animals: | Animals were Holstein and Jersey dairy cattle. |
| Breeds associated:
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| Design: | Animals were genotyped with the Illumina BovineSNP50 BeadChip (or had LD data imputed to 50K) and analyzed for susceptibility to MAP infection. A total of 22,406 SNPs were used for single-marker analysis, while 45,640 SNPs were used for Bayesian analysis. |
| Analysis: | Genome-wide association using mixed model and regression--GC (GRAMMAR-GC) and Bayes C analyses were performed. |
| Software: | GenAbel in R, BEAGLE, GenSel |
| Notes: | |
| Links: | Edit |
| Reference |
|---|
| Authors: | Sallam AM, Zare Y, Alpay F, Shook GE, Collins MT, Alsheikh S, Sharaby M, Kirkpatrick BW |
| Affiliation: | Department of Animal Sciences, College of Agricultural and Life Sciences, University of Wisconsin-Madison, Madison, WI 53706, USA |
| Title: | An across-breed genome wide association analysis of susceptibility to paratuberculosis in dairy cattle |
| Journal: | Journal of Dairy Research, 2017, 84(1): 61-67 |
| Links: |
PubMed | Abstract | List all data
| Edit |
| Additional Information |
|---|
| Comments: | Combined p-values from within-breed analysis |
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