Release 56
(Apr 24, 2025)

QTL 11891 Description:

 Trait Information
Trait name: M. paratuberculosis susceptibility Vertebrate Trait Ontology: n/a
Reported name: M. paratuberculosis susceptibility Product Trait Ontology: n/a
Symbol: MPARA Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:18
QTL Peak Location:23.2 (cM)
QTL Span:27.48-27.68 (cM)
21.4-21.6 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:Association
Model tested:Mendelian
Test base:Comparison-wise
Threshold significance level:Significant
P_values0.040
Dominance effect:n/a
Additive effect:n/a
Associated Gene:NOD2 (nucleotide-binding oligomerization domain containing 2)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Spanish and Dutch Holstein-Friesian cattle.
     Breeds associated:
    Design:Animals were genotyped for 18 SNPs in NOD2 and analyzed for infection with Mycobacterium avium subsp. paratuberculosis
    Analysis:A chi-squared test was used.
    Software:Haploview, SPSS
    Notes: 
    Links:Edit

     Reference
    Authors:Ruiz-Larranaga O, Garrido JM, Iriondo M, Manzano C, Molina E, Koets AP, Rutten VP, Juste RA, Estonba A
    Affiliation:Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country, Sarriena s/n, 48940 Leioa (Bizkaia), Spain
    Title:Genetic association between bovine NOD2 polymorphisms and infection by Mycobacterium avium subsp. paratuberculosis in Holstein-Friesian cattle
    Journal:Animal genetics, 2010, 41(6): 652-5
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:c.*1908 allele C; Dutch population
    User inputs on reference #20477790
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  • Cite this Data:

    Animal QTLdb: QTL11891 was published in 2010, and was curated into QTLdb on 2010-07-15. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:11891

     

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