QTL Map Information |
Chromosome: | 18 |
QTL Peak Location: | 23.2 (cM) |
QTL Span: | 27.48-27.68 (cM) 21.4-21.6 (Mbp) |
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Upper, "Suggestive": | n/a |
Upper, "Significant": | n/a |
Peak: | |
Lower, "Significant": | n/a |
Lower, "Suggestive": | n/a |
Marker type: | |
Analysis type: | Association |
Model tested: | Mendelian |
Test base: | Comparison-wise |
Threshold significance level: | Significant |
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P_values | 0.006 | Dominance effect: | n/a |
Additive effect: | n/a |
Associated Gene: | NOD2 (nucleotide-binding oligomerization domain containing 2) |
Cis/Trans acting type: |  |
Links:
NCBI GeneDB | Edit |
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Extended information: |
(none) |
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QTL Experiment in Brief |
Animals: | Animals were Spanish and Dutch Holstein-Friesian cattle. |
Breeds associated:
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Design: | Animals were genotyped for 18 SNPs in NOD2 and analyzed for infection with Mycobacterium avium subsp. paratuberculosis |
Analysis: | A chi-squared test was used. |
Software: | Haploview, SPSS |
Notes: | |
Links: | Edit |
Reference |
Authors: | Ruiz-Larranaga O, Garrido JM, Iriondo M, Manzano C, Molina E, Koets AP, Rutten VP, Juste RA, Estonba A |
Affiliation: | Department of Genetics, Physical Anthropology and Animal Physiology, University of the Basque Country, Sarriena s/n, 48940 Leioa (Bizkaia), Spain |
Title: | Genetic association between bovine NOD2 polymorphisms and infection by Mycobacterium avium subsp. paratuberculosis in Holstein-Friesian cattle |
Journal: | Animal genetics, 2010, 41(6): 652-5 |
Links: |
PubMed | Abstract | List all data
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Additional Information |
Comments: | c.*1908 allele C; Spanish population |

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