Release 56
(Apr 24, 2025)

QTL 11661 Description:

 Trait Information
Trait name: M. paratuberculosis susceptibility Vertebrate Trait Ontology: n/a
Reported name: M. paratuberculosis susceptibility Product Trait Ontology: n/a
Symbol: MPARA Clinical Measurement Ontology: Disease process measurement
 QTL Map Information
Chromosome:2
QTL Peak Location:94.7 (cM)
QTL Span:58.84-59.04 (cM)
62.2-62.4 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:Association
Model tested:Mendelian
Test base:Experiment-wise
Threshold significance level:Significant
P_values0.023
Dominance effect:n/a
Additive effect:n/a
Associated Gene:SLC11A1 (solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were Holstein-Friesian cattle.
     Breeds associated:
    Design:Animals were genotyped for SNPs in SLC11A1 and analyzed for infection with Mycobacterium avium ssp. paratuberculosis (MAP).
    Analysis:A Chi-square analysis was performed.
    Software:SPSS, Plink, Haploview
    Notes: 
    Links:Edit

     Reference
    Authors:Ruiz-Larraņaga O, Garrido JM, Manzano C, Iriondo M, Molina E, Gil A, Koets AP, Rutten VP, Juste RA, Estonba A
    Affiliation:Genetics, Physical Anthropology, and Animal Physiology Department, University of the Basque Country, Sarriena s/n, 48940 Leioa, Bizkaia, Spain
    Title:Identification of single nucleotide polymorphisms in the bovine solute carrier family 11 member 1 (SLC11A1) gene and their association with infection by Mycobacterium avium subspecies paratuberculosis
    Journal:J Dairy Sci, 2010, 93(4): 1713-21
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:c.1157-91A>T; European Holstein-Friesian
    User inputs on reference #20338449
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  • Cite this Data:

    Animal QTLdb: QTL11661 was published in 2010, and was curated into QTLdb on 2010-04-30. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:11661

     

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