Release 56
(Apr 24, 2025)

QTL 11529 Description:

 Trait Information
Trait name: Rabies antibody titer Vertebrate Trait Ontology: Blood immunoglobulin amount
Reported name: Rabies antibody titer Product Trait Ontology: n/a
Symbol: RABT Clinical Measurement Ontology: Antibody titer
 QTL Map Information
Chromosome:4
QTL Peak Location:78 (cM)
QTL Span:42.67-45.65 (cM)
42.7-45.7 (Mbp)
Upper, "Suggestive":n/a
Upper, "Significant":n/a
Peak:
Lower, "Significant":n/a
Lower, "Suggestive":n/a
Marker type:
Analysis type:Association
Model tested:Mendelian
Test base:n/a
Threshold significance level:Significant
P_values<0.05
Dominance effect:n/a
Additive effect:n/a
Associated Gene:LEP (leptin)
Cis/Trans acting type:
Links:   NCBI GeneDB  |  Edit  |   Map view

 Extended information:
(none)

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  •  QTL Experiment in Brief
    Animals:Animals were mixed-breed beef cattle.
     Breeds associated:
    n/a
    Design:Animals were genotyped for a SNP in leptin and analyzed for immune cell counts and rabies antibody titers prior to and following vaccination.
    Analysis:A mixed linear model was used.
    Software:SAS
    Notes: 
    Links:Edit

     Reference
    Authors:Asiamah PA, Bechtel DG, Waldner C, Buchanan FC
    Affiliation:College of Agriculture and Bioresources, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5A8, Canada
    Title:Effects of leptin Arg25Cys on peripheral mononuclear cell counts and antibody response to vaccination in beef cattle
    Journal:Animal genetics, 2009, 40(5): 783-7
    Links:  PubMed  |  Abstract   |  List all data   |  Edit  

     Additional Information
    Comments:Difference in titer from day 0 to day 21 post-vaccination
    User inputs on reference #19466939
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  • Cite this Data:

    Animal QTLdb: QTL11529 was published in 2009, and was curated into QTLdb on 2010-04-13. DBxREF link to this data: https://www.animalgenome.org/QTLdb/q?id=QTL_ID:11529

     

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