QTL Map Information |
Chromosome: | 18 |
QTL Peak Location: | 83.05 (cM) |
QTL Span: | 83.05-83.05 (cM) 63.4-63.4 (Mbp) |
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Upper, "Suggestive": | n/a |
Upper, "Significant": | n/a |
Peak: | rs42978574 |
Lower, "Significant": | n/a |
Lower, "Suggestive": | n/a |
Marker type: | SNP |
Analysis type: | Association |
Model tested: | Mendelian |
Test base: | n/a |
Threshold significance level: | Significant |
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P_values | 4.47E-11 | Dominance effect: | n/a |
Additive effect: | n/a |
Associated Gene: | n/a |
Cis/Trans acting type: |  |
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Extended information: |
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QTL Experiment in Brief |
Animals: | Animals were Holstein-Friesian cattle.
Animal breed (IDs) involved: 106
Animal breed (IDs) involved: |
Breeds associated:
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Design: | Animals were genotyped using the Illumina BovineHD BeadChip (or had lower-density genotypes imputed to HD) and analyzed for calving interval. Genes differentially expressed between high- and low-fertility groups were analyzed for concordance with significant SNPs from GWAS. |
Analysis: | Univariate animal linear mixed models were used for GWAS. |
Software: | Beagle, WOMBAT, R software |
Notes: | |
Links: | Edit |
Reference |
Authors: | Moore SG, Pryce JE, Hayes BJ, Chamberlain AJ, Kemper KE, Berry DP, McCabe M, Cormican P, Lonergan P, Fair T, Butler ST |
Affiliation: | Animal and Grassland Research and Innovation Centre, Teagasc, Moorepark, Fermoy, County Cork, Ireland |
Title: | Differentially Expressed Genes in Endometrium and Corpus Luteum of Holstein Cows Selected for High and Low Fertility Are Enriched for Sequence Variants Associated with Fertility |
Journal: | Biology of reproduction, 2016, 94(1): 19 |
Links: |
PubMed | Abstract | List all data
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