QTLdb: entrichment tests

Release 56
(Apr 24, 2025)

Whole genome analysis for QTL/association enrichment

Running...

Version: Enrich S: beta v0.8

Search:	to limit the list of your trait choices:
	(optional) focus on chromosome with Mb windows across its length

Data:

Number of behavioral traits:	16
Number of QTL / associations found:	212
Number of chromosomes where QTL / associations are found:	30

Chi-squared (χ²) test: are behavioral traits over-represented on some chromosomes?

Chromosomes	Total χ²	df	p-values	FDR ^*	Size of χ²
Chromosome X	8.46288	29	0.9999281	9.999281e-01
Chromosome 1	35.02896	29	0.2035904	5.552465e-01
Chromosome 2	2.57616	29	0.998329325823115	9.999281e-01
Chromosome 3	0.01008	29	0.998329325823115	9.999281e-01
Chromosome 4	21.29312	29	0.848249	9.999281e-01
Chromosome 5	21.29312	29	0.848249	9.999281e-01
Chromosome 6	2.57616	29	0.998329325823115	9.999281e-01
Chromosome 7	180.68928	29	7.487936e-24	1.123190e-22
Chromosome 8	9.67040	29	0.9997137	9.999281e-01
Chromosome 9	79.70816	29	1.278108e-06	7.668648e-06
Chromosome 10	19.48176	29	0.9083049	9.999281e-01
Chromosome 11	1.97232	29	0.998329325823115	9.999281e-01
Chromosome 12	2.57616	29	0.998329325823115	9.999281e-01
Chromosome 13	83.33088	29	3.730922e-07	2.798191e-06
Chromosome 14	378.72704	29	1.487422e-62	4.462266e-61
Chromosome 15	19.48176	29	0.9083049	9.999281e-01
Chromosome 16	0.01008	29	0.998329325823115	9.999281e-01
Chromosome 17	21.29312	29	0.848249	9.999281e-01
Chromosome 18	58.12320	29	0.001051176	3.941910e-03
Chromosome 19	0.01008	29	0.998329325823115	9.999281e-01
Chromosome 20	58.12320	29	0.001051176	3.941910e-03
Chromosome 21	37.44400	29	0.1352049	4.056147e-01
Chromosome 22	9.67040	29	0.9997137	9.999281e-01
Chromosome 23	37.44400	29	0.1352049	4.056147e-01
Chromosome 24	21.29312	29	0.848249	9.999281e-01
Chromosome 25	1.97232	29	0.998329325823115	9.999281e-01
Chromosome 26	1.97232	29	0.998329325823115	9.999281e-01
Chromosome 27	0.01008	29	0.998329325823115	9.999281e-01
Chromosome 28	58.12320	29	0.001051176	3.941910e-03
Chromosome 29	108.84032	29	3.592969e-11	3.592969e-10

Chi-squared (χ²) test: Which of the 16 behavioral traits are over-represented in the QTLdb

Traits	Total χ²	df	p-values	FDR ^*	Size of χ²
Aggressive behavior	49.24679	15	1.597495e-05	5.111984e-05
Behavior	18.52577	15	0.2360332	2.360332e-01
Calf sucking reflex	96.40755	15	6.232016e-14	9.971226e-13
Duration of activity during novel object test	30.16758	15	0.01133136	1.813018e-02
Duration of activity during open field test	90.51669	15	7.943653e-13	6.354922e-12
Duration of exploration during novel object test	34.45194	15	0.002941067	5.434100e-03
Duration of exploration during open field test	34.33334	15	0.003056681	5.434100e-03
Duration of inactivity during novel object test	22.81702	15	0.08810289	9.397642e-02
Duration of inactivity during open field test	73.27621	15	1.157832e-09	6.175104e-09
Flight from feeder	54.81424	15	1.918849e-06	7.675396e-06
Flight speed	34.7514	15	0.002667475	5.434100e-03
Maternal behavior	26.6149	15	0.03203523	3.942798e-02
Social separation--Standing alert	26.86881	15	0.02982359	3.942798e-02
Social separation--Vocalization	23.69192	15	0.07051333	8.058666e-02
Social separation--Walking/running	26.90093	15	0.02955398	3.942798e-02
Temperament	41.1764	15	0.0003005763	8.015368e-04

Correlations found between some of these traits for your reference

No correlation data found on these traits

Overall Test

Data		Chi'Square Test			Fisher's Exact Test
Number of chrom.:	30	χ²	=	1281.207680
Number of traits:	16	df	=	435
Number of QTLs:	212	p-value	=	2.664738e-84

FOOT NOTE: * : FDR is short for "false discovery rate", representing the expected proportion of type I errors. A type I error is where you incorrectly reject the null hypothesis, i.e. you get a false positive. It's statistical definition is FDR = E(V/R | R > 0) P(R > 0), where V = Number of Type I errors (false positives); R = Number of rejected hypotheses. Benjamini–Hochberg procedure is a practical way to estimate FDR.